Even if renaming a mp4 file to ismv worked, I wouldn't ship GSP with the ismv file support included unless I can do a real test with IIS smooth streaming. I may do that someday, but I have higher priorities for now.
Meanwhile, you can do this yourself if you want, since all you have to do is a couple edits to galleryserverpro.config. (1) Add the .ismv mime type. (2) Add an HTML template in the mediaObject section (based on a copy of the video/mp4 template).
Roger Martin
Creator and Lead Developer of Gallery Server Pro